Multiple vertebral fractures may occur following discontinuation of treatment with Prolia, particularly in patients with a history of vertebral fracture.1
Advise patients not to interrupt Prolia therapy without their physician’s advice.1
Evaluate the individual benefit/risk before discontinuing treatment with Prolia.1
If Prolia treatment is discontinued, consider transitioning to an alternative antiresorptive therapy.1
Additional Resources
References
1. | Prolia Product Monograph. Amgen Canada Inc., December 21, 2022. |